Erica Sparkenbaugh
USA
Erica Sparkenbaugh, PhD is an Assistant Professor in the Department of Pathology and Laboratory Medicine (DPLM) at the University of North Carolina at Chapel Hill. She joined the department in September 2024 and is also faculty in the Pathobiology and Translational Sciences (PBTS) PhD program and a member of the UNC Blood Research Center. Dr. Sparkenbaugh’s research focuses on the mechanisms linking coagulation, inflammation, and vascular complications in blood disorders such as sickle cell disease and β-thalassemia, with an emphasis on translational approaches and women’s health. She earned her BS in Biology from Allegheny College and her PhD in Pharmacology & Toxicology from Michigan State University, and completed postdoctoral training in hematology at UNC Chapel Hill. Her work bridges basic science and clinical relevance to advance understanding of thrombo-inflammatory disease processes.
10:30 – 12:20
Thursday Day 4 : May 7th
Scientific Session 8 – Hemoglobinopathies: Mechanisms
CHAIRS : Maria De Grandis, Andreas Glenthøj
10:30 – 10:55 Invited speaker: Ana Bélen Pérez Oliva (Spain)
Nanomedicine-Based mRNA Therapy to Restore Erythrocyte Maturation in β-Thalassemia
10:55 – 11:20 Invited speaker: Erica Sparkenbaugh (USA)
11:20 – 11:35 Marie Martin (France)
Hematocrit partially explains the hypercoagulable profile of sickle cell patients11:35 – 11:50 Kuntal Dey (Switzerland)
S-glutathionylation inhibits plasma membrane Ca2+ ATPase 4b activity in erythrocytes from healthy subjects and sickle cell patients11:50 – 12:05 Rezin Majied (The Netherlands)
Investigation of RBC dehydration in SCD-derived erythroid progenitor cell lines12:05 – 12:20 Julien Grenier (France)
Ineffective erythropoiesis reshapes erythroid niche in sickle cell disease