speaker-photo

Lars Hanssen

UK
Lars Hanssen is a Clinical Lecturer in Haematology at Imperial College London, with a clinical interest in paediatric haematology. He completed his DPhil at the University of Oxford in the laboratory of Professor Doug Higgs FRS, where his research focused on the regulation of the α-globin locus and the role of chromatin architecture in regulating tissue-specific gene expression during erythropoiesis. He is currently based in the group of Dr Deena Iskander at Imperial College London, where his work centres on the molecular basis underlying the erythropoietic defects observed in Diamond-Blackfan Anaemia Syndrome.​​​​​​​​​​​​​​​​
14:00 – 15:50

Tuesday Day 2 : May 5th

Scientific Session 3 – Disordered Erythropoiesis and Red Cell Pathophysiology

CHAIRS : Deena Iskander, Loane Schertzer

14:00 – 14:25 Invited speaker: Peng Ji (United States)

Erythroblastic islands in physiology and pathology

14:25 – 14:50 Invited speaker: Lars Hanssen (UK)

Mechanisms of disordered erythropoiesis in Diamond-Blackfan Anaemia Syndrome

14:50 – 15:05 Marije Bartels (The Netherlands)

iPSC models are excellent tools to study impaired erythropoiesis and molecular defects in Diamond-Blackfan anemia syndrome (DBAS)

15:05 – 15:20 Smritikana Dutta (India)

Heme tunes proteostasis and oxidative stress signaling through the P. falciparum artemisinin determinant PfKelch13

15:20 – 15:35 Mélanie Franco (France)

Lipid overload of red blood cells, spleen function and congestion are key determinants of splenomegaly in Gaucher disease

15:35 – 15:50 Elena Martinez Balsalobre (Spain)

Modulation of NLRP1 inflammasome as a strategy in congenital sideroblastic anemia